Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 1/20 | 0.56 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.54 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.54 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.51 |
| ▸ | TYR | P14679 | 1/20 | 0.51 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1161802 | 1.00 | ERN1 (0.56) | ERN1HSD17B1HSD17B2TRIM24TYR | |
| SCHEMBL9768767 | 0.87 | TRIM24 (0.56) | ERN1HSD17B1HSD17B2TRIM24TYR | |
| SCHEMBL17980719 | 0.87 | ERN1 (0.56) | ERN1TRIM24TYRTRIM33LMNA | |
| SCHEMBL12472034 | 0.82 | SMN1; SMN2 (0.52) | ERN1LMNAALDH1A1MAPTMEN1 | |
| SCHEMBL18024095 | 0.81 | ALDH1A1 (0.54) | ERN1TRIM24TYRTRIM33HTT | |
| SCHEMBL29954247 | 0.81 | ERN1 (0.49) | ERN1TRIM24TYRTRIM33TSHR | |
| SCHEMBL28504582 | 0.80 | ERN1 (0.58) | ERN1TRIM24TYRTRIM33LMNA | |
| SCHEMBL8887292 | 0.79 | ALDH1A1 (0.59) | ERN1TSHRALDH1A1KMT2AKDM4E | |
| SCHEMBL23117837 | 0.79 | CES2 (0.49) | ERN1TRIM24TYRTRIM33HTT | |
| SCHEMBL1289713 | 0.79 | ALDH1A1 (0.49) | ERN1TRIM24TYRTRIM33LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |