SCHEMBL9768767

SCHEMBL9768767

COc1ccc(C=O)c(NC(C)=O)c1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRIM24 O15164 1/20 0.56
TYR P14679 1/20 0.56
TRIM33 Q9UPN9 1/20 0.56
HTT P42858 4/20 0.55
LMNA P02545 1/20 0.55
TSHR P16473 1/20 0.55
ALDH1A1 P00352 6/20 0.53
ERN1 O75460 1/20 0.51
SMN1; SMN2 Q16637 4/20 0.50
NPC1 O15118 3/20 0.50
RAB9A P51151 3/20 0.50
DYRK1A Q13627 2/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2C19 P33261 1/20 0.50
HSD17B1 P14061 1/20 0.50
HSD17B2 P37059 1/20 0.50
KDM4E B2RXH2 3/20 0.48
MAPT P10636 3/20 0.48
MTNR1A P48039 2/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29951677 0.87 ERN1 (0.56) TRIM24TYRTRIM33HTTLMNA
SCHEMBL1161802 0.87 ERN1 (0.56) TRIM24TYRTRIM33HTTLMNA
SCHEMBL17084899 0.83 TRIM24 (0.51) TRIM24TYRTRIM33LMNATSHR
SCHEMBL30981444 0.83 TRIM24 (0.51) TRIM24TYRTRIM33LMNATSHR
SCHEMBL1931934 0.82 GAA (0.51) HTTLMNATSHRALDH1A1SMN1; SMN2
SCHEMBL1931936 0.82 GAA (0.51) HTTLMNATSHRALDH1A1SMN1; SMN2
SCHEMBL13890889 0.82 MTNR1A (0.49) LMNAALDH1A1ERN1SMN1; SMN2NPC1
SCHEMBL29956858 0.81 TRIM24 (0.49) TRIM24TYRTRIM33LMNAALDH1A1
SCHEMBL28574210 0.81 SNCA (0.61) HTTSMN1; SMN2NPC1RAB9AKDM4E
SCHEMBL6361641 0.79 AKR1C3 (0.65) MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed
US-5071729-A Discoloration inhibitor releasing compound FUJI PHOTO FILM CO., LTD. (JP) 1991-12-10 US disclosed
US-4916047-A POLYMERIC COMPOUND RELEASING USEFUL GROUP BY REDOX PROCESS TRIGGERED BY REDUCING AGENT FUJI PHOTO FILM CO., LTD. (JP) 1990-04-10 US disclosed
US-4877720-A PHOTOGRAPHIC POLYMER WHICH UNDERGOES REDUCTION UPON DEVELOPMENT FUJI PHOTO FILM CO., LTD. (JP) 1989-10-31 US disclosed