SCHEMBL29951697

SCHEMBL29951697

CCNC(=O)CN(CC)c1ccc(C=O)cc1C

nearest known ligand 0.48

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A3 P47895 4/20 0.48
ALDH1A1 P00352 8/20 0.45
ALDH3A1 P30838 5/20 0.44
PKM P14618 1/20 0.34
TSHR P16473 1/20 0.34
HPGD P15428 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29956220 0.88 ALDH1A1 (0.46) ALDH1A3ALDH1A1ALDH3A1PKMTSHR
SCHEMBL29954099 0.88 ALDH1A3 (0.49) ALDH1A3ALDH1A1ALDH3A1HPGDSMN1; SMN2
SCHEMBL29954285 0.85 ALDH1A3 (0.47) ALDH1A3ALDH1A1ALDH3A1SMN1; SMN2
SCHEMBL29951185 0.84 ALDH1A3 (0.46) ALDH1A3ALDH1A1ALDH3A1HPGDL3MBTL1
SCHEMBL9362085 0.82 ALDH1A3 (0.67) ALDH1A3ALDH1A1ALDH3A1TSHRL3MBTL1
SCHEMBL29955092 0.80 ALDH1A1 (0.62) ALDH1A3ALDH1A1ALDH3A1TSHRHPGD
SCHEMBL2561228 0.77 ALDH1A1 (0.39) ALDH1A3ALDH1A1ALDH3A1TSHRHPGD
SCHEMBL2560265 0.77 ALDH1A1 (0.51) ALDH1A3ALDH1A1ALDH3A1SMN1; SMN2
SCHEMBL29955288 0.76 ALDH1A3 (0.38) ALDH1A3ALDH1A1ALDH3A1HPGDL3MBTL1
SCHEMBL29953969 0.76 ALDH1A3 (0.43) ALDH1A3ALDH1A1ALDH3A1TSHRHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220340893-A1 BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES NUEVOLUTION A/S (DK) 2022-10-27 US disclosed