Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | CNR2 | P34972 | 7/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29958150 | 0.84 | UBE2T (0.45) | ALDH1A1CNR2MAPTLMNASMN1; SMN2 | |
| SCHEMBL29952578 | 0.82 | UBE2T (0.44) | ALDH1A1CNR2CYP1A2MAPTHPGD | |
| SCHEMBL15332124 | 0.79 | HRH4 (0.45) | SMN1; SMN2RAB9A | |
| SCHEMBL2556957 | 0.77 | MAPT (0.44) | ALDH1A1MAPTHPGDKDM4EMEN1 | |
| SCHEMBL2562752 | 0.76 | KDM4E (0.43) | ALDH1A1MAPTKDM4EMEN1GAA | |
| SCHEMBL19859753 | 0.75 | POLB (0.51) | ALDH1A1CNR2CYP1A2MAPTHPGD | |
| SCHEMBL29586304 | 0.75 | ALDH1A1 (0.54) | ALDH1A1CNR2CYP1A2MAPTCYP2C9 | |
| SCHEMBL29953385 | 0.75 | ALDH1A1 (0.40) | ALDH1A1CNR2CYP1A2MAPTCYP2C9 | |
| SCHEMBL9147 | 0.75 | ALDH1A1 (0.54) | ALDH1A1CNR2CYP1A2MAPTCYP2C9 | |
| SCHEMBL29952920 | 0.75 | POLB (0.51) | ALDH1A1CNR2CYP1A2MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |