Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19859753 | 1.00 | POLB (0.51) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL21484382 | 0.80 | MAPT (0.45) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL29951749 | 0.75 | ALDH1A1 (0.44) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL102532 | 0.74 | LMNA (0.52) | MAPTALDH1A1MEN1KMT2ARAB9A | |
| SCHEMBL521049 | 0.74 | PIK3CA (0.56) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL18256503 | 0.74 | POLB (0.55) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL22502739 | 0.74 | POLB (0.55) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL5198623 | 0.74 | AKR1C3 (0.70) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL1735452 | 0.74 | CHRNB2 (0.64) | POLBMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL255401 | 0.74 | MAPT (0.55) | POLBMAPTALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |