Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.59 |
| ▸ | MAPT | P10636 | 3/20 | 0.59 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.59 |
| ▸ | TYMS | P04818 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955116 | 0.89 | HSD17B10 (0.59) | HSD17B10MAPTESR2PDE3BPDE3A | |
| SCHEMBL29956595 | 0.84 | KDM4E (0.51) | HSD17B10MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL1039269 | 0.84 | KDM4E (0.51) | HSD17B10MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL29954984 | 0.79 | LMNA (0.47) | HSD17B10MAPTESR2PDE3BPDE3A | |
| SCHEMBL13849761 | 0.77 | FLT3 (0.43) | MAPTALDH1A1KDM4ETSHRKMT2A | |
| SCHEMBL19448889 | 0.75 | DAO (0.60) | HSD17B10MAPTALDH1A1HPGDKDM4E | |
| SCHEMBL21676421 | 0.75 | HSD17B10 (1.00) | HSD17B10MAPTESR2PDE3BPDE3A | |
| SCHEMBL29609392 | 0.74 | ALDH1A1 (0.56) | HSD17B10MAPTPDE3BPDE3AALDH1A1 | |
| SCHEMBL28590063 | 0.74 | ALDH1A1 (0.56) | HSD17B10MAPTPDE3BPDE3AALDH1A1 | |
| SCHEMBL5543703 | 0.73 | HSD17B10 (0.54) | HSD17B10MAPTESR2TYMSPDE3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |