Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.47 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.47 |
| ▸ | FLT3 | P36888 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | ERN1 | O75460 | 1/20 | 0.46 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1039269 | 1.00 | KDM4E (0.51) | KDM4EALDH1A1MAPTCA2CYP1A2 | |
| SCHEMBL2731348 | 0.88 | KDM4E (0.58) | KDM4EALDH1A1MAPTCA2CYP1A2 | |
| SCHEMBL29951789 | 0.84 | HSD17B10 (0.59) | KDM4EALDH1A1MAPTCYP1A2HSD17B10 | |
| SCHEMBL13849761 | 0.81 | FLT3 (0.43) | KDM4EALDH1A1MAPTCYP1A2LMNA | |
| SCHEMBL29956508 | 0.79 | CA2 (0.54) | KDM4EALDH1A1MAPTCA2CYP1A2 | |
| SCHEMBL19448889 | 0.79 | DAO (0.60) | KDM4EALDH1A1MAPTCYP1A2CYP2C19 | |
| SCHEMBL433980 | 0.79 | BRD4 (0.56) | KDM4EALDH1A1MAPTCA2CYP1A2 | |
| SCHEMBL5828348 | 0.79 | CA2 (0.54) | KDM4EALDH1A1MAPTCA2CYP1A2 | |
| SCHEMBL3846232 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1MAPTCYP1A2HSD17B10 | |
| SCHEMBL4377723 | 0.78 | CA2 (0.53) | KDM4EALDH1A1MAPTCA2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |