Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 1/20 | 0.59 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.49 |
| ▸ | APP | P05067 | 1/20 | 0.46 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | METAP2 | P50579 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | COMT | P21964 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432001 | 0.78 | PDPK1 (0.61) | PDPK1DYRK1AAPPACHERET | |
| SCHEMBL6544062 | 0.78 | PDPK1 (0.66) | PDPK1DYRK1AAPPACHERET | |
| SCHEMBL29952061 | 0.78 | ALDH1A1 (0.59) | DYRK1ARAB9AALDH1A1KMT2ATSHR | |
| SCHEMBL74065 | 0.74 | PDPK1 (1.00) | PDPK1DYRK1AAPPACHERET | |
| SCHEMBL5820155 | 0.74 | PDPK1 (0.61) | PDPK1DYRK1AAPPACHERET | |
| SCHEMBL17987894 | 0.74 | PDPK1 (0.61) | PDPK1DYRK1AAPPACHERET | |
| SCHEMBL3622776 | 0.74 | PDPK1 (0.61) | PDPK1DYRK1AAPPACHERET | |
| SCHEMBL10574548 | 0.74 | PSMB8 (0.65) | PDPK1DYRK1AAPPACHERET | |
| SCHEMBL29950761 | 0.74 | ALDH1A1 (0.38) | PDPK1DYRK1ARAB9AALDH1A1KMT2A | |
| SCHEMBL28957121 | 0.73 | MEN1 (0.46) | PDPK1RAB9AALDH1A1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |