Sugi Predict

Sugi Predict / Compounds / SCHEMBL74065

SCHEMBL74065

SCHEMBL74065

Nc1nc2c(O)cccc2s1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ PDPK1 O15530 1/20 1.00
▸ ALDH1A1 P00352 1/20 0.61
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ LMNA P02545 1/20 0.61
▸ PDE10A Q9Y233 1/20 0.61
▸ CYP3A4 P08684 1/20 0.56
▸ TDP1 Q9NUW8 1/20 0.56
▸ NSD1 Q96L73 2/20 0.53
▸ DYRK1A Q13627 1/20 0.50
▸ APP P05067 1/20 0.47
▸ PLAU P00749 1/20 0.46
▸ NCF1 P14598 1/20 0.46
▸ ACHE P22303 1/20 0.43
▸ HTT P42858 2/20 0.43
▸ GAA P10253 1/20 0.43
▸ L3MBTL1 Q9Y468 1/20 0.43
▸ NSD2 O96028 1/20 0.43
▸ NSD3 Q9BZ95 1/20 0.43
▸ CYP2C19 P33261 1/20 0.43
▸ PIK3CD O00329 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6544062 0.79 PDPK1 (0.66) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
SCHEMBL969167 0.79 ALDH1A1 (0.66) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
Hydrochloric Acid SCHEMBL28787382 0.78 ALDH1A1 (0.63) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
SCHEMBL3622776 0.76 PDPK1 (0.61) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
SCHEMBL5432001 0.76 PDPK1 (0.61) PDPK1ALDH1A1SMN1; SMN2DYRK1AAPP
SCHEMBL17987894 0.76 PDPK1 (0.61) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
SCHEMBL5820155 0.76 PDPK1 (0.61) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
SCHEMBL24858578 0.76 ALDH1A1 (0.61) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
SCHEMBL2748892 0.76 ALDH1A1 (0.61) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A
SCHEMBL13050515 0.76 ALDH1A1 (0.61) PDPK1ALDH1A1SMN1; SMN2LMNAPDE10A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 176 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240368505-A1 FLUORINE-FREE CLEANING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF Tan Kah Kee Innovation Laboratory (CN) 2024-11-07 — — US claimed
WO-2023133876-A1 FLUORINE-FREE CLEANING AGENT, PREPARATION METHOD THEREFOR AND USE THEREOF 嘉庚创新实验室 2023-07-20 — — WO claimed
CN-114960229-A Tent cloth dyeing process 圣山集团有限公司 2022-08-30 — — CN claimed
CN-114317127-A Fluoride-free cleaning agent, and preparation method and application thereof 嘉庚创新实验室 2022-04-12 — — CN claimed
CN-110437463-B Dendritic polymer, preparation method and application thereof 威海晨源分子新材料有限公司 2022-01-21 — — CN claimed
CN-106366310-B Carboxyl-containing high-refractive-index hyperbranched polyesteramide, preparation method thereof and application thereof in plastic modification 威海晨源分子新材料有限公司 2020-09-08 — — CN claimed
CN-109021502-B Outer layer hole plugging resin and preparation method thereof 南雄市科鼎化工有限公司 2020-07-31 — — CN claimed
CN-110437463-A Dendritic, preparation method and its application WEIHAI CY DENDRIMER TECH CO LTD 2019-11-12 — — CN claimed
CN-106366310-A Carboxyl-containing high-refractive-index hyperbranched polyesteramide and preparation method thereof, as well as application of carboxyl-containing high-refractive-index hyperbranched polyesteramide to plastic modification 威海晨源分子新材料有限公司 2017-02-01 — — CN claimed
CN-103103586-A Thiazole compound-containing copper electroplating solution UNIV SHAANXI NORMAL 2013-05-15 — — CN claimed
US-20250382273-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS INST NAT SANTE RECH MED (FR) 2025-12-18 — — US disclosed
CN-117126578-B Organosilicon polymer/POSS hybrid antifouling coating grafted with antibacterial molecules and preparation method thereof 中国科学院海洋研究所 2025-04-22 — — CN disclosed
WO-2025026903-A1 IMIDAZO PYRIMIDINE COMPOUNDS FOR THE TREATMENT OF CANCER BAYER AKTIENGESELLSCHAFT (DE) 2025-02-06 — — WO disclosed
WO-2024230578-A1 CYCLIC DERIVATIVES, COMPOSITIONS AND USES THEREOF DANATLAS PHARMACEUTICALS CO., LTD. (CN) 2024-11-14 — — WO disclosed
EP-4460500-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE - INSERM (FR) 2024-11-13 — — EP disclosed
EP-1112275-A1 NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE Metabasis Therapeutics, Inc. (US) 2001-07-04 — — EP disclosed
WO-2000038666-A2 A COMBINATION OF FBPase INHIBITORS AND INSULIN SENSITIZERS FOR THE TREATMENT OF DIABETES METABASIS THERAPEUTICS, INC. (US) 2000-07-06 — — WO disclosed
WO-2000014095-A1 NOVEL HETEROAROMATIC INHIBITORS OF FRUCTOSE 1,6-BISPHOSPHATASE METABASIS THERAPEUTICS, INC. (US) 2000-03-16 — — WO disclosed
US-4046770-A IMMUNE REGULANTS ELI LILLY AND COMPANY (US) 1977-09-06 — — US disclosed
US-3932434-A IMMUNOSUPPRESSANTS ELI LILLY AND COMPANY (US) 1976-01-13 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382273-A1 BENZOTHIAZOLE ANAOLOGUES AND USE THEREOF AS BOOSTERS OF ANTI TUBERCULOSIS DRUGS BBOX1, NDUFB6, NDUFB5 PDPK1 3763/4885ALDH1A1 108/4885SMN1; SMN2 4416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.