Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | LPL | P06858 | 2/20 | 0.41 |
| ▸ | LIPG | Q9Y5X9 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951590 | 0.90 | KDM4E (0.58) | ENPP2KDM4ETSHRESR1KMT2A | |
| SCHEMBL2559125 | 0.86 | TSHR (0.52) | ENPP2KDM4ETSHRESR1LPL | |
| SCHEMBL2551679 | 0.85 | ENPP2 (0.50) | ENPP2KDM4ETSHRCHRNB2CHRNA4 | |
| SCHEMBL7992 | 0.84 | ENPP2 (0.59) | ENPP2KDM4ETSHRLPLLIPG | |
| SCHEMBL2561927 | 0.83 | ENPP2 (0.45) | ENPP2KDM4ETSHRCHRNB2CHRNA4 | |
| SCHEMBL3652437 | 0.83 | CHRNB2 (0.64) | ENPP2KDM4ECHRNB2CHRNA4ESR1 | |
| SCHEMBL177358 | 0.83 | ENPP2 (0.58) | ENPP2TSHRLPLLIPG | |
| SCHEMBL2552738 | 0.82 | KDM4E (0.54) | ENPP2KDM4ETSHRCHRNB2CHRNA4 | |
| SCHEMBL29954521 | 0.81 | LPL (0.57) | ENPP2TSHRLPLLIPGKMT2A | |
| SCHEMBL29954450 | 0.81 | BCHE (0.48) | ENPP2ESR1BCHEACHELPL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |