Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.66 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.66 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | EPAS1 | Q99814 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30093157 | 0.87 | CHRNB2 (0.79) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 | |
| SCHEMBL29955815 | 0.85 | CHRNB2 (0.62) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 | |
| SCHEMBL10028665 | 0.83 | CHRNB2 (0.85) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 | |
| SCHEMBL29954574 | 0.82 | LPL (0.47) | CHRNB2CHRNA4KDM4EACHEMAOB | |
| SCHEMBL12663150 | 0.82 | LPL (0.50) | ALDH1A1KDM4ELMNAACHEMAOB | |
| SCHEMBL12195600 | 0.81 | CHRNB2 (0.69) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 | |
| SCHEMBL6674571 | 0.80 | CHRNB2 (1.00) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 | |
| SCHEMBL31044635 | 0.80 | CHRNB2 (1.00) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 | |
| SCHEMBL3239914 | 0.80 | CHRNB2 (0.67) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 | |
| SCHEMBL29954523 | 0.79 | CHRNB2 (0.58) | CHRNB2CHRNA4MAPK1CHRNA7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |