Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 7/20 | 0.47 |
| ▸ | LIPG | Q9Y5X9 | 7/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.40 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.40 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | CXCR1 | P25024 | 2/20 | 0.37 |
| ▸ | CXCR2 | P25025 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30093206 | 0.84 | KDM4E (0.53) | KDM4ESMN1; SMN2CHRNB2CHRNA4POLB | |
| SCHEMBL27947483 | 0.82 | SMN1; SMN2 (0.50) | KDM4ESMN1; SMN2CHRNB2CHRNA4CYP1A2 | |
| SCHEMBL29953749 | 0.82 | ENPP2 (0.49) | LPLLIPGKDM4ESMN1; SMN2CHRNB2 | |
| SCHEMBL29951815 | 0.82 | CHRNB2 (0.66) | KDM4ESMN1; SMN2CHRNB2CHRNA4ACHE | |
| SCHEMBL12663150 | 0.81 | LPL (0.50) | LPLLIPGKDM4ESMN1; SMN2CA2 | |
| SCHEMBL19697830 | 0.80 | PYCR1 (0.51) | LPLLIPGCA2CA1F11 | |
| SCHEMBL7197772 | 0.78 | LPL (0.50) | LPLLIPGCA2CA1F11 | |
| SCHEMBL29951011 | 0.78 | KDM4E (0.52) | KDM4ESMN1; SMN2POLBCXCR1CXCR2 | |
| SCHEMBL171670 | 0.77 | PYCR1 (0.53) | KDM4ESMN1; SMN2CHRNB2CHRNA4 | |
| SCHEMBL29957724 | 0.77 | KDM4E (0.43) | LIPGKDM4ESMN1; SMN2CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |