Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMO | O15229 | 2/20 | 0.70 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 2/20 | 0.61 |
| ▸ | RXRB | P28702 | 2/20 | 0.61 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 1/20 | 0.53 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.53 |
| ▸ | MAP4K5 | Q9Y4K4 | 1/20 | 0.53 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | CA6 | P23280 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3015814 | 1.00 | KMO (0.70) | KMOLMNAGAARXRARXRB | |
| SCHEMBL10389918 | 0.91 | MAP4K4 (0.59) | KMOLMNAGAAMAP4K4CSNK1G2 | |
| SCHEMBL5517654 | 0.90 | KMO (0.69) | KMOLMNAGAARXRARXRB | |
| SCHEMBL2943938 | 0.90 | KMO (0.63) | KMOLMNAGAARXRARXRB | |
| SCHEMBL407605 | 0.89 | KMO (0.67) | KMOLMNAGAAMAP4K4CSNK1G2 | |
| SCHEMBL29446517 | 0.89 | KMO (0.67) | KMOLMNAGAAMAP4K4CSNK1G2 | |
| SCHEMBL246827 | 0.89 | CA12 (0.58) | KMOGAACA12CA1CA2 | |
| SCHEMBL29902348 | 0.89 | CA12 (0.58) | KMOGAACA12CA1CA2 | |
| SCHEMBL2586835 | 0.89 | KMO (0.59) | KMOLMNAGAAMAP4K4CSNK1G2 | |
| SCHEMBL71238 | 0.89 | KMO (0.86) | KMOLMNAGAARXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |