SCHEMBL407605

SCHEMBL407605

CC(=O)c1cccc(-c2ccccc2)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMO O15229 1/20 0.67
MAPT P10636 2/20 0.65
SMN1; SMN2 Q16637 1/20 0.65
HDAC8 Q9BY41 1/20 0.60
MAP4K4 O95819 1/20 0.58
CSNK1G2 P78368 1/20 0.58
CLK4 Q9HAZ1 1/20 0.58
MKNK2 Q9HBH9 1/20 0.58
MAP4K5 Q9Y4K4 1/20 0.58
HDAC2 Q92769 1/20 0.58
KMT2A Q03164 2/20 0.56
MEN1 O00255 1/20 0.56
ERCC5 P28715 1/20 0.55
FEN1 P39748 1/20 0.55
LMNA P02545 1/20 0.54
GAA P10253 1/20 0.54
TDP1 Q9NUW8 1/20 0.54
CHEK1 O14757 1/20 0.54
PRSS1 P07477 1/20 0.53
PRSS2 P07478 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29446517 1.00 KMO (0.67) KMOMAPTSMN1; SMN2HDAC8MAP4K4
SCHEMBL2586835 0.96 KMO (0.59) KMOMAPTSMN1; SMN2HDAC8MAP4K4
SCHEMBL10389918 0.93 MAP4K4 (0.59) KMOMAPTSMN1; SMN2HDAC8MAP4K4
SCHEMBL10389377 0.89 MAPT (0.69) KMOMAPTSMN1; SMN2MAP4K4CSNK1G2
SCHEMBL29951818 0.89 KMO (0.70) KMOMAPTSMN1; SMN2MAP4K4CSNK1G2
SCHEMBL3015814 0.89 KMO (0.70) KMOMAPTSMN1; SMN2MAP4K4CSNK1G2
Acetophenone SCHEMBL27984785 0.89 MAPT (0.68) KMOMAPTSMN1; SMN2HDAC8MAP4K4
SCHEMBL2943938 0.88 KMO (0.63) KMOMAPTSMN1; SMN2HDAC2KMT2A
Biphenyl SCHEMBL1555184 0.86 MAPT (0.86) KMOMAPTSMN1; SMN2HDAC2LMNA
SCHEMBL4572428 0.86 NPC1 (0.56) KMOMAPTSMN1; SMN2MAP4K4CSNK1G2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4464696-A1 CHEMICALLY DEGRADABLE EPOXY COMPOUND, METHOD FOR PREPARING SAME, EPOXY COMPOSITE MATERIAL COMPRISING SAME, AND DECOMPOSITION METHOD THEREOF Konkuk University Industrial Cooperation Corp. (KR) 2024-11-20 EP claimed
US-20230365742-A1 CHEMICALLY DEGRADABLE EPOXY COMPOUND, METHOD OF PREPARING SAME COMPOUND, EPOXY COMPOSITE MATERIAL CONTAINING SAME COMPOUND, AND METHOD OF DEGRADING SAME COMPOSITE MATERIAL KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP (KR) 2023-11-16 US claimed
CN-106117113-A Polysubstituted carbazole, derivant and synthetic method thereof 湘潭大学 2016-11-16 CN claimed
CN-106046281-A FUNCTIONALIZED KETONE-ALDEHYDE CONDENSATION RESINS 赢创德固赛有限公司 2016-10-26 CN claimed
EP-2785754-B1 PHOTOACTIVE RESINS, RADIATION CURABLE COMPOSITIONS AND RADIATION CURABLE INKS SUN CHEMICAL CORP (US) 2016-07-06 EP claimed
US-20140315002-A1 PHOTOACTIVE RESINS, RADIATION CURABLE COMPOSITIONS AND RADIATION CURABLE INKS SUN CHEMICAL CORPORATION (US) 2014-10-23 US claimed
EP-2785754-A1 PHOTOACTIVE RESINS, RADIATION CURABLE COMPOSITIONS AND RADIATION CURABLE INKS Sun Chemical Corporation (US) 2014-10-08 EP claimed
WO-2013082262-A1 PHOTOACTIVE RESINS, RADIATION CURABLE COMPOSITIONS AND RADIATION CURABLE INKS SUN CHEMICAL CORPORATION (US) 2013-06-06 WO claimed
EP-4712750-A2 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE Idemitsu Kosan Co.,Ltd. (JP) 2026-03-18 EP disclosed
US-20250230167-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2025-07-17 US disclosed
US-12312317-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device IDEMITSU KOSAN CO., LTD. (JP) 2025-05-27 US disclosed
CN-119998272-A Methanogen inhibitors 阿格里泽伦茨有限合伙公司 2025-05-13 CN disclosed
CN-115052872-B Compound, material for organic electroluminescent element, and electronic device 出光兴产株式会社 2025-02-18 CN disclosed
CN-113825735-B Carbon-carbon bond formation method 奥加诺株式会社 2025-01-07 CN disclosed
US-4256758-A 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione inhibitors of glycolic acid oxidase MERCK & CO., INC. (US) 1981-03-17 US disclosed
EP-0021228-A1 4-Substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same MERCK & CO. INC. (US) 1981-01-07 EP disclosed
US-4226887-A P-BIPHENYLYLACETYLENE ELI LILLY AND COMPANY (US) 1980-10-07 US disclosed
US-3991212-A PHENYLACETYLENE COMPOUNDS ELI LILLY AND COMPANY (US) 1976-11-09 US disclosed
US-3968251-A Arylacetylene compounds as antithrombotic agents ELI LILLY AND COMPANY (US) 1976-07-06 US disclosed
US-3939278-A Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents ELI LILLY AND COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250230167-A1 COMPOUND, MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, AND ELECTRONIC DEVICE PIEZO1, LEF1, L1CAM KMO 3797/4885MAPT 1646/4885SMN1; SMN2 2652/4885
US-12312317-B2 Compound, material for organic electroluminescent elements, organic electroluminescent element, and electronic device PIEZO1, LEF1, L1CAM KMO 3772/4885MAPT 1595/4885SMN1; SMN2 2672/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.