Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.46 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 1/20 | 0.41 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.41 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.41 |
| ▸ | PAK4 | O96013 | 1/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.41 |
| ▸ | CSF1R | P07333 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.41 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16920112 | 1.00 | PIM1 (0.46) | PIM1PIM3LMNAHPGDGSK3B | |
| SCHEMBL29952323 | 0.86 | GSK3B (0.51) | PIM1PIM3GSK3BJAK2GSK3A | |
| SCHEMBL29363428 | 0.82 | LMNA (0.51) | LMNAHPGDMAPTCHUKALDH1A1 | |
| SCHEMBL22898794 | 0.82 | LMNA (0.51) | LMNAHPGDMAPTCHUKALDH1A1 | |
| SCHEMBL24522320 | 0.79 | KDM4E (0.44) | LMNAHPGDMAPTCHUKALDH1A1 | |
| SCHEMBL3198006 | 0.79 | LMNA (0.51) | PIM1PIM3LMNAHPGDGSK3B | |
| SCHEMBL28460398 | 0.79 | PIM1 (0.46) | PIM1PIM3LMNAHPGDGSK3B | |
| SCHEMBL24522294 | 0.79 | KDM4E (0.46) | LMNAHPGDMAPTHSD17B10ALDH1A1 | |
| SCHEMBL29363427 | 0.79 | KDM4E (0.46) | LMNAHPGDMAPTHSD17B10ALDH1A1 | |
| SCHEMBL29950892 | 0.79 | CCNB2 (0.53) | GSK3BCHEK1FLT3GSK3ACDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |