Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNB2 | O95067 | 1/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.53 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.53 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.40 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.40 |
| ▸ | TOP1 | P11387 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22898794 | 0.82 | LMNA (0.51) | GAAMEN1KMT2A | |
| SCHEMBL29363428 | 0.82 | LMNA (0.51) | GAAMEN1KMT2A | |
| SCHEMBL29951828 | 0.79 | PIM1 (0.46) | KMT2ACDK5DYRK1AGSK3AGSK3B | |
| SCHEMBL29363427 | 0.79 | KDM4E (0.46) | GAAMEN1POLBKMT2AACHE | |
| SCHEMBL24522320 | 0.79 | KDM4E (0.44) | GAAMEN1KMT2AACHE | |
| SCHEMBL24522294 | 0.79 | KDM4E (0.46) | GAAMEN1POLBKMT2AACHE | |
| SCHEMBL29951087 | 0.79 | GAA (0.54) | GAAMEN1POLBCASP6KMT2A | |
| SCHEMBL16920112 | 0.79 | PIM1 (0.46) | KMT2ACDK5DYRK1AGSK3AGSK3B | |
| SCHEMBL26323678 | 0.79 | MAPT (0.39) | CCNB2CDK1CCNB1CCNB3MEN1 | |
| SCHEMBL20138843 | 0.76 | ALDH1A1 (0.56) | CCNB2CDK1CCNB1CCNB3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |