Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | PLK4 | O00444 | 2/20 | 0.41 |
| ▸ | PLK1 | P53350 | 2/20 | 0.41 |
| ▸ | PLK2 | Q9NYY3 | 1/20 | 0.41 |
| ▸ | PLK3 | Q9H4B4 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 2/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | MPO | P05164 | 1/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27815827 | 0.83 | PLK4 (0.50) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL22898794 | 0.82 | LMNA (0.51) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL29363428 | 0.82 | LMNA (0.51) | KDM4EALDH1A1GLAGAAMAPT | |
| SCHEMBL29363427 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL16920112 | 0.79 | PIM1 (0.46) | ALDH1A1MAPTMAPK1LMNAHPGD | |
| SCHEMBL2062443 | 0.79 | KEAP1 (0.51) | KDM4EALDH1A1GLAGAAHTT | |
| SCHEMBL29950892 | 0.79 | CCNB2 (0.53) | GAAACHEMEN1KMT2A | |
| SCHEMBL24522294 | 0.79 | KDM4E (0.46) | KDM4EALDH1A1GAAMAPTMAPK1 | |
| SCHEMBL29951828 | 0.79 | PIM1 (0.46) | ALDH1A1MAPTMAPK1LMNAHPGD | |
| SCHEMBL20625430 | 0.79 | DAO (0.48) | KDM4EALDH1A1GLAGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114206857-B | Benzofuranyl N-acylhydrazone derivatives and pharmaceutical compositions comprising the same | 韩国生命工学研究院 | 2024-09-06 | — | — | CN | disclosed |
| US-20230293487-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2023-09-21 | — | — | US | disclosed |
| US-20230293487-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2023-09-21 | — | — | US | disclosed |
| EP-4186503-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | Korea Research Institute of Bioscience and Biotechnology (KR) | 2023-05-31 | — | — | EP | disclosed |
| CN-116157120-A | Anti-inflammatory compositions comprising benzofuranyl N-acylhydrazone derivatives | 韩国生命工学研究院 | 2023-05-23 | — | — | CN | disclosed |
| EP-4015516-A1 | BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVE AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | Korea Research Institute of Bioscience and Biotechnology (KR) | 2022-06-22 | — | — | EP | disclosed |
| CN-114206857-A | Benzofuranyl N-acylhydrazone derivatives and pharmaceutical compositions containing the same | 韩国生命工学研究院 | 2022-03-18 | — | — | CN | disclosed |
| WO-2022019663-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | 한국생명공학연구원 | 2022-01-27 | — | — | WO | disclosed |
| CN-101747254-B | Substituent indole compound and application thereof | SHENYANG RES INST CHEMICAL IND | 2012-07-04 | — | — | CN | disclosed |
| CN-101747254-A | Substituent indole compound and application thereof | SHENYANG RES INST CHEMICAL IND | 2010-06-23 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230293487-A1 | ANTI-INFLAMMATORY COMPOSITION COMPRISING BENZOFURAN-BASED N-ACYLHYDRAZONE DERIVATIVES | RELA, NFKBIA, IKBKG | KDM4E 2006/4885ALDH1A1 1094/4885GLA 2152/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.