Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SNCA | P37840 | 2/20 | 0.44 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.42 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 2/20 | 0.41 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.41 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA4 | P22748 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.39 |
| ▸ | PIM1 | P11309 | 1/20 | 0.39 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957172 | 0.88 | CA2 (0.43) | MAOAMAOBTP53ALDH1A1SNCA | |
| SCHEMBL29952126 | 0.84 | MAOB (0.43) | MAOAMAOBTP53ALDH1A1PIM1 | |
| SCHEMBL29952427 | 0.79 | EPHX2 (0.40) | ALDH1A1CA2CA12CA1CA4 | |
| SCHEMBL15730582 | 0.79 | MAOA (0.51) | MAOAMAOBTP53ALDH1A1SNCA | |
| SCHEMBL18901276 | 0.78 | MAOA (0.46) | MAOAMAOBTP53ALDH1A1SNCA | |
| SCHEMBL30067792 | 0.76 | TP53 (0.57) | MAOAMAOBTP53ALDH1A1CDYL2 | |
| SCHEMBL17066902 | 0.76 | TP53 (0.57) | MAOAMAOBTP53ALDH1A1CDYL2 | |
| SCHEMBL29953205 | 0.76 | PGR (0.43) | TP53CDYL2CDYLMEN1LMNA | |
| SCHEMBL29954649 | 0.76 | TP53 (0.46) | TP53ALDH1A1CA2CA12CA1 | |
| SCHEMBL14555907 | 0.75 | MAOB (0.57) | MAOAMAOBTP53ALDH1A1SNCA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |