Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.52 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.52 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.52 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | SUV39H2 | Q9H5I1 | 7/20 | 0.46 |
| ▸ | CKS1B | P61024 | 1/20 | 0.45 |
| ▸ | SKP1 | P63208 | 1/20 | 0.45 |
| ▸ | SKP2 | Q13309 | 1/20 | 0.45 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12694575 | 1.00 | PIM1 (0.52) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL31073157 | 0.93 | CKS1B (0.49) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL29952159 | 0.90 | PIM1 (0.44) | PIM1PIM3PIM2CTSKCKS1B | |
| SCHEMBL3708015 | 0.86 | CTSK (0.52) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL22434715 | 0.86 | CTSK (0.52) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL22434601 | 0.86 | CTSK (0.52) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL29951119 | 0.86 | PIM1 (0.49) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL14418346 | 0.86 | CTSK (0.50) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL12841264 | 0.85 | SUV39H2 (0.52) | PIM1PIM3PIM2CTSKSUV39H2 | |
| SCHEMBL30936771 | 0.85 | CTSK (0.51) | PIM1PIM3PIM2CTSKSUV39H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |