Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1642304 | 0.82 | ACHE (0.37) | ACHETSHRLRRK2DAO | |
| SCHEMBL6065091 | 0.78 | ALDH1A1 (0.40) | ACHETSHRHTT | |
| SCHEMBL29353234 | 0.78 | ALDH1A1 (0.40) | ACHETSHRHTT | |
| SCHEMBL31727453 | 0.77 | HDAC1 (0.37) | HDAC1HDAC6ACHEMAPTNISCH | |
| SCHEMBL8921670 | 0.73 | CYP3A4 (0.46) | MAPT | |
| SCHEMBL997705 | 0.73 | RAPGEF4 (0.34) | MAPTLRRK2KMO | |
| SCHEMBL29954727 | 0.73 | KDM1A (0.37) | LRRK2 | |
| SCHEMBL29954363 | 0.73 | CYP3A4 (0.46) | MAPT | |
| SCHEMBL12446575 | 0.73 | ESR1 (0.38) | HSD17B10 | |
| SCHEMBL1106569 | 0.73 | ALDH1A1 (0.50) | HDAC1HDAC6LRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |