Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 2/20 | 0.40 |
| ▸ | TTR | P02766 | 2/20 | 0.39 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | F12 | P00748 | 1/20 | 0.36 |
| ▸ | F11 | P03951 | 1/20 | 0.36 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.36 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.36 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.36 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | TDO2 | P48775 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953773 | 0.85 | ENPP2 (0.43) | ENPP2TTRNR4A2PLGF12 | |
| SCHEMBL25338825 | 0.80 | NR4A2 (0.61) | ENPP2EGFRTTRNR4A2PLG | |
| SCHEMBL20600556 | 0.80 | SMN1; SMN2 (0.47) | ENPP2EGFRTTRNR4A2PLG | |
| SCHEMBL20292848 | 0.80 | TTR (0.50) | ENPP2EGFRTTRNR4A2PLG | |
| SCHEMBL29945144 | 0.77 | NR4A2 (0.61) | NR4A2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL3268768 | 0.77 | NR4A2 (0.61) | NR4A2MAPTMEN1ALDH1A1KMT2A | |
| SCHEMBL30819181 | 0.76 | PARP1 (0.47) | ENPP2NR4A2MAPTKDM4EERN1 | |
| SCHEMBL1332713 | 0.76 | PARP1 (0.47) | ENPP2NR4A2MAPTKDM4EERN1 | |
| SCHEMBL22125565 | 0.76 | ENPP2 (0.42) | ENPP2EGFRTTRNR4A2KDM4E | |
| SCHEMBL30379753 | 0.76 | HTR1A (0.43) | ENPP2EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |