Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | PLG | P00747 | 1/20 | 0.39 |
| ▸ | F12 | P00748 | 1/20 | 0.39 |
| ▸ | F11 | P03951 | 1/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | TTR | P02766 | 2/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.33 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951934 | 0.85 | ENPP2 (0.43) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL19957245 | 0.80 | TTR (0.46) | ENPP2PLGF12F11KLKB1 | |
| SCHEMBL29958114 | 0.76 | KDM4E (0.42) | NR4A2GAAMAPT | |
| SCHEMBL29509132 | 0.76 | TLR8 (0.54) | ENPP2TLR8NR4A2SOS2GAA | |
| SCHEMBL28164080 | 0.76 | TLR8 (0.54) | ENPP2TLR8NR4A2SOS2GAA | |
| SCHEMBL29952242 | 0.74 | ENPP2 (0.55) | ENPP2TTRCA1CA2MAPT | |
| SCHEMBL856485 | 0.74 | ENPP2 (0.55) | ENPP2TTRCA1CA2MAPT | |
| SCHEMBL1490718 | 0.73 | ALK (0.50) | PLGTLR8 | |
| SCHEMBL8601956 | 0.73 | GAK (0.42) | TLR8NR4A2SOS2GAAMAPT | |
| SCHEMBL2658022 | 0.73 | HTR1A (0.54) | TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |