Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.42 |
| ▸ | GABRD | O14764 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.42 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.42 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.42 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.42 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.42 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.42 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.42 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.42 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.42 |
| ▸ | GABRE | P78334 | 1/20 | 0.42 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.42 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.42 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.42 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.42 |
| ▸ | ERN1 | O75460 | 4/20 | 0.36 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4276322 | 1.00 | CYP2A6 (0.42) | CYP2A6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL15223704 | 0.81 | MTNR1A (0.38) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL2608546 | 0.78 | CYP2A6 (0.46) | CYP2A6MAPT | |
| SCHEMBL19114247 | 0.78 | CYP2A6 (0.46) | CYP2A6 | |
| SCHEMBL12392404 | 0.78 | KMT2A (0.40) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL3994517 | 0.76 | AXL (0.49) | CYP2A6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4266872 | 0.76 | GABRP (0.53) | CYP2A6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL4268436 | 0.75 | CYP2A6 (0.46) | CYP2A6GABRPGABRDGABRA1GABRB1 | |
| SCHEMBL31733036 | 0.73 | PIN1 (0.51) | GABRPGABRDGABRA1GABRB1GABRG2 | |
| SCHEMBL15223896 | 0.73 | PDGFRB (0.42) | GABRPGABRDGABRA1GABRB1GABRG2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |