Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 3/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 3/20 | 0.41 |
| ▸ | HTR6 | P50406 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | SRC | P12931 | 1/20 | 0.37 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.37 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.37 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5716679 | 0.81 | HDAC3 (0.51) | CXCL8NOD1HTR6POLBL3MBTL1 | |
| SCHEMBL3530924 | 0.77 | PPARG (0.58) | ALDH1A1 | |
| SCHEMBL3529707 | 0.76 | PPARG (0.62) | — | |
| SCHEMBL5716686 | 0.76 | MAPT (0.45) | CXCL8NOD1POLBALDH3A1ALDH1A1 | |
| SCHEMBL5716683 | 0.75 | CA12 (0.44) | CXCL8NOD1HTR6POLBL3MBTL1 | |
| SCHEMBL5716691 | 0.74 | ALDH3A1 (0.41) | CXCL8NOD1HTR6POLBL3MBTL1 | |
| SCHEMBL5716773 | 0.74 | TUBB4A (0.52) | ALDH1A1MEN1KMT2AHDAC3HDAC4 | |
| SCHEMBL5716735 | 0.74 | HDAC3 (0.59) | CXCL8NOD1HTR6POLBL3MBTL1 | |
| SCHEMBL2932847 | 0.74 | CA12 (0.51) | CXCL8NOD1HTR6ALDH1A1HPGD | |
| SCHEMBL29953049 | 0.74 | CA12 (0.51) | CXCL8NOD1HTR6ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |