Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.51 |
| ▸ | CA9 | Q16790 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | SRC | P12931 | 2/20 | 0.46 |
| ▸ | CCR2 | P41597 | 1/20 | 0.46 |
| ▸ | HTR6 | P50406 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | NOD1 | Q9Y239 | 5/20 | 0.44 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932847 | 1.00 | CA12 (0.51) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL29951130 | 0.88 | NOD1 (0.57) | CA12CA9CA2ALDH1A1CCR2 | |
| SCHEMBL17673234 | 0.88 | NOD1 (0.55) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL29952922 | 0.83 | ALDH1A1 (0.42) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL28059442 | 0.79 | CA12 (0.55) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL20746813 | 0.78 | CA12 (0.51) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL28228343 | 0.77 | CA12 (0.56) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL3563271 | 0.77 | CA12 (0.56) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL6864332 | 0.76 | RECQL (0.73) | CA12CA9CA2ALDH1A1LMNA | |
| SCHEMBL31599460 | 0.76 | CCR2 (0.72) | CA12CA9CA2ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |