Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.37 |
| ▸ | HSD17B3 | P37058 | 15/20 | 0.37 |
| ▸ | PRF1 | P14222 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29951586 | 0.88 | PRF1 (0.42) | KDM4EHTTSMN1; SMN2NOTUMHSD17B3 | |
| SCHEMBL2627990 | 0.80 | DDB1 (0.44) | KDM4EPRF1 | |
| SCHEMBL29955852 | 0.76 | ACACB (0.43) | KDM4EPRF1 | |
| SCHEMBL31373871 | 0.74 | KDM4E (0.59) | KDM4EHTTSMN1; SMN2NOTUMHSD17B3 | |
| SCHEMBL29956886 | 0.74 | ALDH1A1 (0.42) | KDM4EHTTPRF1 | |
| SCHEMBL29952168 | 0.72 | NPC1 (0.59) | KDM4EHTTSMN1; SMN2 | |
| SCHEMBL2559394 | 0.72 | KDM4E (0.43) | KDM4ESMN1; SMN2PRF1 | |
| SCHEMBL29953994 | 0.71 | KDM4E (0.37) | KDM4E | |
| SCHEMBL28586692 | 0.68 | PBRM1 (0.58) | — | |
| SCHEMBL29957631 | 0.68 | HSD17B3 (0.44) | KDM4EHTTSMN1; SMN2NOTUMHSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |