Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | FAP | Q12884 | 1/20 | 0.33 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.33 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.33 |
| ▸ | PRF1 | P14222 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956886 | 0.88 | ALDH1A1 (0.42) | KDM4EALDH1A1HPGDADAM17ALOX15 | |
| SCHEMBL29955396 | 0.88 | PRF1 (0.40) | ACACBKDM4EHDAC4HDAC1HDAC6 | |
| SCHEMBL2559394 | 0.84 | KDM4E (0.43) | KDM4EALDH1A1HPGDHDAC4HDAC1 | |
| SCHEMBL29953994 | 0.82 | KDM4E (0.37) | KDM4EALDH1A1HPGDHDAC4HDAC1 | |
| SCHEMBL2627990 | 0.80 | DDB1 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL10274610 | 0.78 | ACACB (0.44) | ACACBKDM4EALDH1A1HPGDHDAC4 | |
| SCHEMBL29956413 | 0.77 | LMNA (0.42) | KDM4EALDH1A1HDAC6ALOX15TSHR | |
| SCHEMBL8241980 | 0.76 | PARK7 (0.47) | ACACBADAM17 | |
| SCHEMBL21421527 | 0.76 | ADAM17 (0.48) | ACACBKDM4EALDH1A1HPGDHDAC4 | |
| SCHEMBL1952399 | 0.76 | ALDH1A1 (0.57) | ACACBKDM4EALDH1A1HPGDHDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |