Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TKT | P29401 | 1/20 | 0.37 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.33 |
| ▸ | DHFR | P00374 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.31 |
| ▸ | MAT2A | P31153 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17247903 | 0.78 | LMNA (0.40) | HSP90AA1HSP90AB1P2RX7KDM4ECXCR4 | |
| SCHEMBL16635491 | 0.78 | LMNA (0.34) | P2RX7KDM4ECXCR4MGLLTRPV4 | |
| SCHEMBL13260558 | 0.78 | LMNA (0.34) | P2RX7KDM4ECXCR4MGLLTRPV4 | |
| SCHEMBL29955918 | 0.78 | MGLL (0.33) | P2RX7KDM4ECXCR4MGLLTRPV4 | |
| SCHEMBL1040845 | 0.77 | MGLL (0.32) | P2RX7KDM4EMGLLHSD17B10TRPV4 | |
| SCHEMBL29951212 | 0.77 | MGLL (0.32) | P2RX7KDM4EMGLLHSD17B10TRPV4 | |
| SCHEMBL28012819 | 0.77 | IDH1 (0.34) | P2RX7KDM4EMGLLTRPV4LMNA | |
| SCHEMBL14844546 | 0.74 | MBOAT4 (0.36) | KDM4EHSD17B10ALDH1A1KMT2A | |
| SCHEMBL14929718 | 0.74 | — | — | |
| SCHEMBL17986994 | 0.74 | HSP90AA1 (0.44) | TKTHSP90AA1HSP90AB1P2RX7KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |