Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADH1A | P07327 | 3/20 | 0.45 |
| ▸ | ADH1C | P00326 | 2/20 | 0.45 |
| ▸ | ADH4 | P08319 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 12/20 | 0.42 |
| ▸ | DRD2 | P14416 | 5/20 | 0.38 |
| ▸ | DRD4 | P21917 | 4/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957217 | 0.87 | ADH1A (0.48) | ADH1AADH1CADH4DRD3DRD2 | |
| SCHEMBL29951598 | 0.86 | SLC6A4 (0.44) | ADH1AADH1CADH4DRD3DRD2 | |
| SCHEMBL29954588 | 0.83 | DRD3 (0.43) | ADH1AADH1CADH4DRD3DRD2 | |
| SCHEMBL23469783 | 0.81 | — | — | |
| SCHEMBL3376550 | 0.80 | DRD3 (0.50) | DRD3DRD2DRD4HTR1AFYN | |
| SCHEMBL29951894 | 0.77 | ADH1C (0.31) | ADH1AADH1CADH4 | |
| SCHEMBL29952368 | 0.77 | SLC6A2 (0.35) | ADH1AADH1CADH4 | |
| SCHEMBL737468 | 0.76 | — | — | |
| SCHEMBL3370178 | 0.75 | — | — | |
| SCHEMBL21101650 | 0.74 | DRD3 (0.37) | ADH1AADH1CDRD3DRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |