Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.38 |
| ▸ | PPM1A | P35813 | 2/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | GPR3 | P46089 | 3/20 | 0.37 |
| ▸ | ACP1 | P24666 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956515 | 0.88 | TRPV1 (0.43) | KIF11PPM1AMTNR1AMTNR1BGPR3 | |
| SCHEMBL29951136 | 0.84 | ACP1 (0.41) | KIF11PIM1GPR3ACP1TRPV1 | |
| SCHEMBL29952009 | 0.81 | MAPT (0.37) | MTNR1AMTNR1BKMT2AMRGPRX4 | |
| SCHEMBL4080967 | 0.80 | CYP1A2 (0.52) | MTNR1AMTNR1B | |
| SCHEMBL29955414 | 0.80 | CYP1A2 (0.52) | MTNR1AMTNR1B | |
| SCHEMBL16289920 | 0.79 | CYP1A2 (0.52) | KIF11PIM1PPM1AMTNR1AMTNR1B | |
| SCHEMBL17288377 | 0.76 | KIF11 (0.43) | KIF11PIM1PPM1AMTNR1AMTNR1B | |
| SCHEMBL4074876 | 0.76 | KIF11 (0.45) | KIF11PIM1PPM1AGPR3KDM4E | |
| SCHEMBL16289917 | 0.76 | KIF11 (0.45) | KIF11PIM1PPM1AGPR3KDM4E | |
| SCHEMBL29955583 | 0.76 | MGLL (0.49) | KIF11GAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |