Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | ERN1 | O75460 | 3/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | TERT | O14746 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.34 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.34 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956166 | 0.86 | ALDH1A1 (0.46) | MAPTALDH1A1ERN1CYP2A6TERT | |
| SCHEMBL901928 | 0.79 | ALDH1A1 (0.53) | MAPTALDH1A1CYP2A6MEN1KMT2A | |
| SCHEMBL8127634 | 0.78 | L3MBTL1 (0.40) | MAPTALDH1A1ERN1CYP2A6TERT | |
| SCHEMBL20773114 | 0.78 | MAPT (0.40) | MAPTALDH1A1ERN1CYP2A6TERT | |
| SCHEMBL26644028 | 0.77 | MAPT (0.39) | MAPTALDH1A1ERN1CYP2A6TERT | |
| SCHEMBL30644442 | 0.77 | MAPT (0.39) | MAPTALDH1A1ERN1CYP2A6TERT | |
| SCHEMBL18399227 | 0.77 | ALDH1A1 (0.33) | MAPTALDH1A1NFE2L2ERN1TERT | |
| SCHEMBL25187916 | 0.74 | ALDH1A1 (0.41) | MAPTALDH1A1ERN1CYP2A6TERT | |
| SCHEMBL29953532 | 0.74 | ALDH1A1 (0.41) | MAPTALDH1A1ERN1CYP2A6TERT | |
| SCHEMBL31148379 | 0.73 | MAPT (0.36) | MAPTALDH1A1ERN1CYP2A6TERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024258897-A1 | ALKOXYPYRIDINYL AND RELATED COMPOUNDS AND THEIR USE IN THERAPY | DEM BIOPHARMA, INC. (US) | 2024-12-19 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |