Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.43 |
| ▸ | ERN1 | O75460 | 2/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | CCR1 | P32246 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20773114 | 0.87 | MAPT (0.40) | ALDH1A1MAPTCYP2A6ERN1APP | |
| SCHEMBL8127634 | 0.87 | L3MBTL1 (0.40) | ALDH1A1MAPTCYP2A6ERN1APP | |
| SCHEMBL29952233 | 0.86 | MAPT (0.39) | ALDH1A1MAPTCYP2A6ERN1APP | |
| SCHEMBL26644028 | 0.86 | MAPT (0.39) | ALDH1A1MAPTCYP2A6ERN1APP | |
| SCHEMBL30644442 | 0.86 | MAPT (0.39) | ALDH1A1MAPTCYP2A6ERN1APP | |
| SCHEMBL31148379 | 0.81 | MAPT (0.36) | ALDH1A1MAPTCYP2A6ERN1APP | |
| SCHEMBL28418121 | 0.80 | TERT (0.44) | ALDH1A1MAPTERN1TERTKDM4E | |
| SCHEMBL16752604 | 0.78 | HSP90AA1 (0.48) | ALDH1A1MAPTCYP2A6ERN1APP | |
| SCHEMBL3939843 | 0.77 | TERT (0.42) | ALDH1A1TERTKDM4E | |
| SCHEMBL29955053 | 0.76 | APP (0.39) | ALDH1A1MAPTCYP2A6ERN1APP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |