Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 4/20 | 0.55 |
| ▸ | TTR | P02766 | 3/20 | 0.45 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL856485 | 1.00 | ENPP2 (0.55) | ENPP2TTRCA2CA1ALDH1A1 | |
| Hydrochloric Acid SCHEMBL994032 | 0.98 | ENPP2 (0.53) | ENPP2TTRCA2CA1ALDH1A1 | |
| SCHEMBL14421550 | 0.81 | KMT2A (0.37) | ENPP2ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL12419218 | 0.77 | KMT2A (0.39) | ENPP2ALDH1A1MAPTHPGDMEN1 | |
| SCHEMBL360458 | 0.75 | NPC1 (0.57) | ENPP2CA2CA1ALDH1A1MAPT | |
| SCHEMBL3719246 | 0.75 | ALDH1A1 (0.39) | ENPP2ALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL317300 | 0.75 | ALDH1A1 (0.58) | ENPP2CA2CA1ALDH1A1MAPT | |
| SCHEMBL29952779 | 0.75 | NPC1 (0.57) | ENPP2CA2CA1ALDH1A1MAPT | |
| SCHEMBL29953773 | 0.74 | ENPP2 (0.43) | ENPP2TTRCA2CA1MAPT | |
| Hydrochloric Acid SCHEMBL12506154 | 0.74 | ALDH1A1 (0.56) | ENPP2CA2CA1ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025049746-A1 | COMPOSITIONS COMPRISING WERNER SYNDROME HELICASE INHIBITORS AND METHODS OF USING THE SAME | EIKON THERAPEUTICS, INC. (US) | 2025-03-06 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |