Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 2/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 2/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.31 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.31 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.31 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.31 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | ERN1 | O75460 | 1/20 | 0.30 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29956407 | 0.88 | KDM4E (0.37) | PTGS2PTGS1MAPK14 | |
| SCHEMBL15332489 | 0.86 | HSD17B10 (0.33) | PTGS2PTGS1GCGRMAPK14MAPK13 | |
| SCHEMBL15330797 | 0.85 | TYR (0.39) | GCGRMAPK14MAPK13MAPK12MAPK11 | |
| SCHEMBL29954926 | 0.84 | GCGR (0.34) | GCGRMAPK14 | |
| SCHEMBL15331684 | 0.83 | PTGS2 (0.34) | PTGS2PTGS1ERN1 | |
| SCHEMBL29958596 | 0.83 | FEN1 (0.39) | MAPK14ERN1 | |
| SCHEMBL15332033 | 0.81 | ERN1 (0.36) | PTGS2PTGS1ERN1 | |
| SCHEMBL15332415 | 0.79 | CNR1 (0.39) | PTGS2 | |
| SCHEMBL2562293 | 0.79 | PTGS2 (0.36) | ADORA2AADORA2BPTGS2CYP2A6PTGS1 | |
| SCHEMBL29951634 | 0.78 | KDM4E (0.38) | ADORA2AADORA2BPTGS2CYP2A6ERN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |