Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FEN1 | P39748 | 2/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.35 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.35 |
| ▸ | CSNK1E | P49674 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 3/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | PRKDC | P78527 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29955461 | 0.86 | CNR1 (0.40) | ERN1CDC7 | |
| SCHEMBL15331531 | 0.85 | BRD4 (0.35) | MAPK14PTGESALOX5ERN1 | |
| SCHEMBL15333244 | 0.84 | TP53 (0.41) | CSNK1DCSNK1EMAPK14PTGESALOX5 | |
| SCHEMBL29952269 | 0.83 | ADORA2A (0.33) | MAPK14ERN1 | |
| SCHEMBL2551809 | 0.82 | PTGES (0.36) | FEN1CSNK1DCSNK1EMAPK14PTGES | |
| SCHEMBL15331684 | 0.81 | PTGS2 (0.34) | ERN1 | |
| SCHEMBL29953116 | 0.81 | KDM4E (0.37) | PTGESALOX5ERN1CDC7PBRM1 | |
| SCHEMBL2559575 | 0.80 | PTGES (0.37) | CSNK1DCSNK1EMAPK14PTGESALOX5 | |
| SCHEMBL15332033 | 0.80 | ERN1 (0.36) | FEN1ERN1 | |
| SCHEMBL2555973 | 0.80 | MAP2 (0.42) | FEN1CSNK1DCSNK1EMAPK14PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |