Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | LIPE | Q05469 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2031080 | 0.85 | ENPP2 (0.42) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL29782342 | 0.85 | ENPP2 (0.42) | ENPP2ORAI1ORAI2ORAI3LIPE | |
| SCHEMBL14746822 | 0.82 | ENPP2 (0.57) | ENPP2KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL29469117 | 0.82 | ENPP2 (0.57) | ENPP2KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL29954596 | 0.80 | ENPP2 (0.41) | ENPP2KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL2452517 | 0.80 | ALDH1A1 (0.42) | ENPP2KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL29953320 | 0.79 | ENPP2 (0.40) | ENPP2KMT2AORAI1ORAI2ORAI3 | |
| SCHEMBL29427098 | 0.79 | ENPP2 (0.63) | ENPP2ORAI1ORAI2ORAI3SMN1; SMN2 | |
| SCHEMBL126401 | 0.79 | ENPP2 (0.63) | ENPP2ORAI1ORAI2ORAI3SMN1; SMN2 | |
| SCHEMBL29956495 | 0.76 | ENPP2 (0.39) | ENPP2KMT2AHTTSMN1; SMN2LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |