Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.64 |
| ▸ | BCHE | P06276 | 3/20 | 0.59 |
| ▸ | ACHE | P22303 | 2/20 | 0.59 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | GAA | P10253 | 3/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270518 | 1.00 | KMT2A (0.64) | KMT2ABCHEACHERAD51CYP1A2 | |
| SCHEMBL10062253 | 0.91 | CYP1A2 (0.62) | KMT2ABCHEACHERAD51CYP1A2 | |
| SCHEMBL12655119 | 0.85 | KMT2A (0.78) | KMT2ABCHEACHERAD51CYP1A2 | |
| SCHEMBL6204732 | 0.83 | RAD51 (0.79) | KMT2ARAD51ALDH1A1MAPTGAA | |
| SCHEMBL7973772 | 0.83 | RAD51 (0.69) | KMT2ABCHEACHERAD51CYP1A2 | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.80 | ALDH1A1 (0.76) | KMT2ABCHEACHERAD51CYP1A2 | |
| SCHEMBL3302167 | 0.80 | KMT2A (0.69) | KMT2ABCHEACHERAD51CYP1A2 | |
| SCHEMBL31061553 | 0.80 | KMT2A (0.69) | KMT2ABCHEACHECYP1A2ALDH1A1 | |
| SCHEMBL20958113 | 0.79 | SRC (0.56) | KMT2AALDH1A1MAPTGAASMN1; SMN2 | |
| SCHEMBL8048626 | 0.79 | CYP1A2 (0.76) | KMT2ABCHEACHERAD51CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |