Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | BCHE | P06276 | 1/20 | 0.52 |
| ▸ | ACHE | P22303 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2270518 | 0.91 | KMT2A (0.64) | CYP1A2RAD51KMT2AALDH1A1MAPT | |
| SCHEMBL29952313 | 0.91 | KMT2A (0.64) | CYP1A2RAD51KMT2AALDH1A1MAPT | |
| SCHEMBL8048626 | 0.85 | CYP1A2 (0.76) | CYP1A2RAD51KMT2AALDH1A1MAPT | |
| SCHEMBL6204732 | 0.83 | RAD51 (0.79) | RAD51KMT2AALDH1A1MAPTKDM4E | |
| SCHEMBL7973772 | 0.83 | RAD51 (0.69) | CYP1A2RAD51KMT2AALDH1A1MAPT | |
| SCHEMBL2555186 | 0.81 | MAPK1 (0.51) | CYP1A2KMT2AALDH1A1MAPTSMN1; SMN2 | |
| Phenyl Phenylcarbamate SCHEMBL272994 | 0.80 | ALDH1A1 (0.76) | CYP1A2RAD51KMT2AALDH1A1MAPT | |
| SCHEMBL1569274 | 0.80 | CYP1A2 (0.68) | CYP1A2RAD51KMT2AALDH1A1MAPT | |
| SCHEMBL3989104 | 0.80 | CYP1A2 (0.68) | CYP1A2RAD51KMT2AALDH1A1MAPT | |
| SCHEMBL15651741 | 0.79 | TP53 (0.61) | KMT2AMAPTHTTSMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | ZERIA PHARMACEUTICAL CO., LTD. (JP) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010401-A1 | METHOD FOR MANUFACTURING 1,5-BENZODIAZEPINE DERIVATIVE | GABRA5, CYP3A5, GABRA1 | CYP1A2 38/4885RAD51 2058/4885KMT2A 883/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.