Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.30 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.30 |
| ▸ | KMO | O15229 | 1/20 | 0.30 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.30 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.30 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.30 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.30 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.30 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL997705 | 1.00 | RAPGEF4 (0.34) | RAPGEF4ALDH1A1TDP1SLC6A3MAPT | |
| SCHEMBL29957252 | 0.82 | MEN1 (0.38) | RAPGEF4ALDH1A1TDP1SLC6A3MAPT | |
| SCHEMBL12446580 | 0.82 | MEN1 (0.38) | RAPGEF4ALDH1A1TDP1SLC6A3MAPT | |
| SCHEMBL2922332 | 0.78 | CES2 (0.36) | TDP1LRRK2 | |
| SCHEMBL2916024 | 0.78 | AHR (0.43) | ALDH1A1TDP1MAPK1 | |
| SCHEMBL12204625 | 0.77 | APP (0.35) | RAPGEF4SLC6A3SLC6A4SLC6A2 | |
| SCHEMBL13053993 | 0.73 | HSD17B10 (0.50) | ALDH1A1TDP1MAPK1 | |
| SCHEMBL12446575 | 0.73 | ESR1 (0.38) | — | |
| SCHEMBL12619110 | 0.73 | — | — | |
| SCHEMBL29951899 | 0.73 | HDAC1 (0.37) | MAPTKMOLRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |