Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 7/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | RXRA | P19793 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.62 |
| ▸ | MEN1 | O00255 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | POLB | P06746 | 3/20 | 0.53 |
| ▸ | HPGD | P15428 | 3/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | RXRB | P28702 | 3/20 | 0.52 |
| ▸ | RXRG | P48443 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | BCHE | P06276 | 1/20 | 0.51 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.49 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.49 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1125006 | 0.86 | KDM4E (0.60) | KDM4EL3MBTL1NPC1RAB9ABCHE | |
| SCHEMBL28129638 | 0.86 | KDM4E (0.60) | KDM4EL3MBTL1NPC1RAB9ABCHE | |
| SCHEMBL23383976 | 0.82 | RXRA (0.70) | KMT2ATDP1RXRAALDH1A1MEN1 | |
| SCHEMBL2562705 | 0.81 | KMT2A (0.59) | KMT2ATDP1ALDH1A1MEN1POLB | |
| SCHEMBL29953305 | 0.81 | KMT2A (0.66) | KMT2ARXRAALDH1A1MEN1KDM4E | |
| SCHEMBL6341223 | 0.81 | KMT2A (0.66) | KMT2ARXRAALDH1A1MEN1KDM4E | |
| SCHEMBL10900536 | 0.80 | NPC1 (0.54) | KMT2ATDP1KDM4ENPC1RAB9A | |
| SCHEMBL696160 | 0.79 | NPC1 (0.55) | TDP1ALDH1A1HPGDL3MBTL1NPC1 | |
| SCHEMBL18102841 | 0.79 | KMT2A (1.00) | KMT2ATDP1ALDH1A1MEN1KDM4E | |
| SCHEMBL8797996 | 0.78 | KMT2A (0.48) | KMT2ATDP1RXRAALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |