Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7603391 | 0.74 | ALDH1A1 (0.66) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL1429358 | 0.74 | ALDH1A1 (1.00) | ALDH1A1LMNAMAPTKDM4ENPSR1 | |
| SCHEMBL7601837 | 0.73 | ALDH1A1 (0.68) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL8659535 | 0.72 | ALDH1A1 (0.69) | ALDH1A1LMNAMAPTKMT2AKDM4E | |
| SCHEMBL8662170 | 0.71 | LMNA (0.54) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL27158201 | 0.70 | ALDH1A1 (0.46) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL29374992 | 0.69 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL2168491 | 0.69 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4EMAOANPSR1 | |
| SCHEMBL1092518 | 0.69 | ALDH1A1 (0.60) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL10821003 | 0.69 | ALDH1A1 (0.77) | ALDH1A1LMNAMAPTMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |