Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.66 |
| ▸ | LMNA | P02545 | 2/20 | 0.66 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7601837 | 0.84 | ALDH1A1 (0.68) | ALDH1A1LMNAMAOAATMHSD17B10 | |
| SCHEMBL13931827 | 0.80 | ALDH1A1 (0.62) | ALDH1A1LMNAMAOAHSD17B10CYP2C19 | |
| SCHEMBL1429358 | 0.80 | ALDH1A1 (1.00) | ALDH1A1LMNAATMHSD17B10CYP2C19 | |
| SCHEMBL7603632 | 0.79 | LMNA (0.70) | ALDH1A1LMNAMAOAATMHSD17B10 | |
| SCHEMBL7603198 | 0.76 | ALDH1A1 (0.65) | ALDH1A1LMNAMAOAHSD17B10CYP2C19 | |
| SCHEMBL13931828 | 0.76 | ALDH1A1 (0.65) | ALDH1A1LMNAMAOAHSD17B10CYP2C19 | |
| SCHEMBL11688604 | 0.75 | ALDH1A1 (0.63) | ALDH1A1LMNAMAOAHSD17B10CYP2C19 | |
| SCHEMBL10821003 | 0.75 | ALDH1A1 (0.77) | ALDH1A1LMNAATMHSD17B10CYP2C19 | |
| SCHEMBL7796764 | 0.75 | ALDH1A1 (0.55) | ALDH1A1LMNANPSR1SMN1; SMN2MAPT | |
| SCHEMBL29952393 | 0.74 | ALDH1A1 (0.58) | ALDH1A1LMNAMAOAATMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1264825-A1 | Beta-Hydroxyalkylpicoliniumsalts | Bayer Aktiengesellschaft (DE) | 2002-12-11 | — | — | EP | disclosed |
| US-5840902-A | REACTING PICOLINE WITH ALKYLENE OXIDE IN PRESENCE OF ACID IN WATER OR MIXTURE OF WATER AND POLAR SOLVENT | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-24 | — | — | US | disclosed |
| EP-0776888-A2 | Process for the preparation of beta-Hydrosyalkylpicolinium salts and picolinium salts as intermediates for the prepation of cationic dyes | BAYER AG (DE) | 1997-06-04 | — | — | EP | disclosed |