Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 8/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 9/20 | 0.46 |
| ▸ | PRKACA | P17612 | 8/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 7/20 | 0.46 |
| ▸ | CDK5 | Q00535 | 7/20 | 0.46 |
| ▸ | GSK3B | P49841 | 7/20 | 0.46 |
| ▸ | PRKD3 | O94806 | 6/20 | 0.46 |
| ▸ | CLK2 | P49760 | 6/20 | 0.46 |
| ▸ | MAP4K2 | Q12851 | 6/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 6/20 | 0.46 |
| ▸ | GSK3A | P49840 | 6/20 | 0.46 |
| ▸ | CDK8 | P49336 | 5/20 | 0.46 |
| ▸ | CLK4 | Q9HAZ1 | 5/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 4/20 | 0.46 |
| ▸ | CAMK2A | Q9UQM7 | 4/20 | 0.46 |
| ▸ | TAOK1 | Q7L7X3 | 4/20 | 0.46 |
| ▸ | NTRK3 | Q16288 | 4/20 | 0.46 |
| ▸ | NTRK2 | Q16620 | 4/20 | 0.46 |
| ▸ | PAK4 | O96013 | 4/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29953748 | 0.89 | LRRK2 (0.57) | LRRK2KMT2AROCK1PRKACAMAP4K4 | |
| SCHEMBL29957196 | 0.80 | KMT2A (0.56) | LRRK2KMT2AROCK1PRKACAMAP4K4 | |
| SCHEMBL22923901 | 0.78 | LRRK2 (0.54) | LRRK2ROCK1PRKACAMAP4K4CDK5 | |
| SCHEMBL29952060 | 0.77 | LRRK2 (0.50) | LRRK2ROCK1PRKACAMAP4K4CDK5 | |
| SCHEMBL29935820 | 0.77 | KMT2A (0.49) | LRRK2KMT2AROCK1PRKACAMAP4K4 | |
| SCHEMBL21428928 | 0.77 | KMT2A (0.49) | LRRK2KMT2AROCK1PRKACAMAP4K4 | |
| SCHEMBL29958532 | 0.76 | KMT2A (0.47) | LRRK2KMT2AROCK1PRKACAMAP4K4 | |
| SCHEMBL29953901 | 0.76 | KMT2A (0.47) | LRRK2KMT2AROCK1PRKACAMAP4K4 | |
| SCHEMBL29956460 | 0.76 | KMT2A (0.47) | LRRK2KMT2AROCK1PRKACAMAP4K4 | |
| SCHEMBL22096096 | 0.74 | LRRK2 (0.50) | LRRK2ROCK1PRKACAMAP4K4CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |