Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.55 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | HIF1A | Q16665 | 4/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.47 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | MEF2D | Q14814 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6352816 | 0.82 | ENPP2 (0.58) | ENPP2MGLLKDM4EMEN1ALDH1A1 | |
| SCHEMBL10054970 | 0.81 | HDAC8 (0.61) | HDAC8HDAC6HIF1AHDAC4MEF2D | |
| SCHEMBL4382932 | 0.80 | HTT (0.58) | ENPP2MGLLMEN1ALDH1A1GAA | |
| SCHEMBL177678 | 0.80 | FFAR1 (0.54) | ENPP2HIF1AMGLLMEN1KMT2A | |
| SCHEMBL25404519 | 0.77 | CACNA1B (0.53) | KDM4EALDH1A1FFAR1FFAR4 | |
| SCHEMBL3724201 | 0.77 | ENPP2 (0.60) | ENPP2MGLLKDM4EALDH1A1MAPT | |
| SCHEMBL9454973 | 0.77 | HDAC8 (0.57) | HDAC8HDAC6HIF1AHDAC4MEF2D | |
| SCHEMBL11514391 | 0.77 | FFAR1 (0.63) | HDAC8HDAC6HIF1AMAPTL3MBTL1 | |
| SCHEMBL4699374 | 0.77 | HIF1A (0.77) | HDAC8HDAC6HIF1AHDAC4MEF2D | |
| SCHEMBL25880865 | 0.77 | ENPP2 (0.60) | ENPP2CXCR1CXCR2MGLLKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |