Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 3/20 | 0.51 |
| ▸ | CA2 | P00918 | 3/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | PTPRZ1 | P23471 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL177678 | 0.92 | FFAR1 (0.54) | HTTCYP1A2FFAR1FFAR4CA1 | |
| SCHEMBL25405243 | 0.85 | CA1 (0.64) | FFAR1FFAR4CA1CA2MEN1 | |
| SCHEMBL1924100 | 0.83 | HTT (0.78) | HTTALDH1A1CYP1A2CYP2D6FFAR1 | |
| SCHEMBL29950965 | 0.81 | CXCR1 (0.59) | ALDH1A1MEN1GAAMAPTBLM | |
| SCHEMBL29952491 | 0.80 | ENPP2 (0.55) | ALDH1A1FFAR1FFAR4MEN1GAA | |
| SCHEMBL6356134 | 0.80 | TRPV1 (0.58) | CA1CA2TRPV1MEN1KMT2A | |
| SCHEMBL15332273 | 0.80 | MAOB (0.45) | FFAR1MEN1MAPTKMT2AENPP2 | |
| SCHEMBL22628164 | 0.79 | HTT (0.71) | HTTALDH1A1CYP1A2CYP2D6FFAR1 | |
| N-Benzylaniline SCHEMBL7840 | 0.79 | HTT (0.71) | HTTALDH1A1CYP1A2CYP2D6FFAR1 | |
| SCHEMBL158251 | 0.78 | MAPT (0.72) | HTTALDH1A1CYP1A2CYP2D6FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-8299290-B2 | Boron containing functionalizing agent | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2012-10-30 | — | — | US | disclosed |
| US-20120029234-A1 | BORON CONTAINING FUNCTIONALIZING AGENT | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2012-02-02 | — | — | US | disclosed |
| US-8063152-B2 | Boron containing functionalizing agent | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2011-11-22 | — | — | US | disclosed |
| US-7629340-B2 | N-(6-membered aromatic ring)-amido anti-viral compounds | SMITHKLINE BEECHAM CORPORATION (US) | 2009-12-08 | — | — | US | disclosed |
| US-20090229729-A1 | BORON CONTAINING FUNCTIONALIZING AGENT | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2009-09-17 | — | — | US | disclosed |
| EP-1976829-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2008-10-08 | — | — | EP | disclosed |
| US-20070265262-A1 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. | 2007-11-15 | — | — | US | disclosed |
| WO-2007070556-A2 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | GENELABS TECHNOLOGIES, INC. (US) | 2007-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090229729-A1 | BORON CONTAINING FUNCTIONALIZING AGENT | BOLA2; BOLA2B, RBBP4, BRPF1 | HTT 1753/4885ALDH1A1 2624/4885CYP1A2 907/4885 |
| US-20120029234-A1 | BORON CONTAINING FUNCTIONALIZING AGENT | BOLA2; BOLA2B, RBBP4, BRPF1 | HTT 1753/4885ALDH1A1 2624/4885CYP1A2 907/4885 |
| US-20070265262-A1 | N-(6-MEMBERED AROMATIC RING)-AMIDO ANTI-VIRAL COMPOUNDS | ZC3HAV1, HAVCR2, ZC3HAV1L | HTT 3141/4885ALDH1A1 4167/4885CYP1A2 2802/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.