Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.41 |
| ▸ | CCR5 | P51681 | 1/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.36 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | ACVRL1 | P37023 | 2/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22516999 | 1.00 | CCR1 (0.41) | CCR1CCR5CCR8TRIM24TRIM33 | |
| SCHEMBL6852501 | 0.75 | TDP1 (0.46) | TRIM24TRIM33LMNATDP1KMT2A | |
| SCHEMBL25354311 | 0.74 | CCR1 (0.35) | CCR1CCR5CCR8TRIM24TRIM33 | |
| SCHEMBL30453860 | 0.74 | CCR1 (0.35) | CCR1CCR5CCR8TRIM24TRIM33 | |
| SCHEMBL13399609 | 0.72 | ACVRL1 (0.33) | ACVRL1BMPR1BBMPR1AACVR1BTGFBR1 | |
| SCHEMBL3201059 | 0.71 | NCF1 (0.32) | ACVRL1BMPR1BBMPR1AACVR1BTGFBR1 | |
| SCHEMBL4820283 | 0.71 | BMPR1B (0.32) | ACVRL1BMPR1BBMPR1AACVR1BTGFBR1 | |
| SCHEMBL7704567 | 0.71 | PRKCI (0.34) | ACVRL1BMPR1BBMPR1AACVR1BTGFBR1 | |
| SCHEMBL13382187 | 0.70 | ACVRL1 (0.32) | ACVRL1 | |
| SCHEMBL3194003 | 0.69 | KDM4E (0.41) | LMNATDP1KMT2AMEN1THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695236-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | Soley Therapeutics, Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| WO-2024216094-A1 | SUBSTITUTED PHENYL-PIPERAZINYL BASED MODULATORS FOR THE TREATMENT OF DISEASE | SOLEY THERAPEUTICS, INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |