Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 5/20 | 0.42 |
| ▸ | PDE10A | Q9Y233 | 7/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.38 |
| ▸ | TYR | P14679 | 1/20 | 0.38 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NNMT | P40261 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | PDE2A | O00408 | 2/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6792316 | 1.00 | ERN1 (0.42) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL14032801 | 0.80 | NNMT (0.50) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL29935910 | 0.80 | NNMT (0.50) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL1534756 | 0.78 | ERN1 (0.52) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL29952654 | 0.78 | ERN1 (0.52) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL23046187 | 0.78 | ERN1 (0.42) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL10322362 | 0.77 | ERN1 (0.41) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL15228338 | 0.77 | ALDH1A1 (0.45) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL21327305 | 0.77 | ERN1 (0.41) | ERN1PDE10AALDH1A1TRIM24TYR | |
| SCHEMBL7413638 | 0.77 | ERN1 (0.48) | ERN1ALDH1A1TRIM24TYRTRIM33 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |