Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 4/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | PDE10A | Q9Y233 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.39 |
| ▸ | TYR | P14679 | 1/20 | 0.39 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.39 |
| ▸ | BRD7 | Q9NPI1 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | NNMT | P40261 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1534756 | 1.00 | ERN1 (0.52) | ERN1TDP1POLBPDE10AALDH1A1 | |
| SCHEMBL3571476 | 0.84 | ALDH1A1 (0.55) | ERN1TDP1POLBPDE10AALDH1A1 | |
| SCHEMBL28632784 | 0.83 | ERN1 (0.40) | ERN1TDP1POLBPDE10AALDH1A1 | |
| SCHEMBL2415421 | 0.82 | PRKDC (0.40) | ERN1TDP1POLBALDH1A1TRIM24 | |
| SCHEMBL9831052 | 0.82 | ALDH1A1 (0.41) | ERN1TDP1ALDH1A1TRIM24TYR | |
| SCHEMBL29935910 | 0.82 | NNMT (0.50) | ERN1TDP1POLBPDE10AALDH1A1 | |
| SCHEMBL14032801 | 0.82 | NNMT (0.50) | ERN1TDP1POLBPDE10AALDH1A1 | |
| SCHEMBL28868578 | 0.81 | ERN1 (0.42) | ERN1TDP1POLBALDH1A1TRIM24 | |
| SCHEMBL23046187 | 0.80 | ERN1 (0.42) | ERN1TDP1POLBPDE10AALDH1A1 | |
| SCHEMBL28153665 | 0.80 | ERN1 (0.46) | ERN1TDP1POLBPDE10AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115836075-A | Aza-and aza-thio-coumarin derivatives for use in optically active devices | 爱尔兰眼力健公司 | 2023-03-21 | — | — | CN | disclosed |
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |