Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 1/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | TLR6 | Q9Y2C9 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.38 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SRC | P12931 | 2/20 | 0.34 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21643943 | 0.78 | ALDH1A1 (0.53) | TLR2ERN1TLR1TLR6POLB | |
| SCHEMBL29953356 | 0.78 | KAT2B (0.50) | TLR2ERN1TLR1TLR6POLB | |
| SCHEMBL29956551 | 0.77 | POLB (0.37) | POLB | |
| SCHEMBL29952700 | 0.76 | MCHR1 (0.39) | TLR2ERN1TLR1TLR6POLB | |
| SCHEMBL16305430 | 0.76 | HPGD (0.50) | TLR2ERN1TLR1TLR6POLB | |
| SCHEMBL29951973 | 0.75 | CA12 (0.43) | TLR2ERN1TLR1TLR6POLB | |
| SCHEMBL29954655 | 0.75 | CA1 (0.39) | TLR2ERN1TLR1TLR6POLB | |
| SCHEMBL29956373 | 0.75 | KAT2B (0.38) | POLBKAT2BBAZ2BALDH1A1HPGD | |
| SCHEMBL20064340 | 0.74 | PDE4A (0.46) | KAT2BBAZ2BSMN1; SMN2HRH1MCHR1 | |
| SCHEMBL29951166 | 0.74 | ERN1 (0.41) | TLR2ERN1TLR1TLR6POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |