Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 4/20 | 0.54 |
| ▸ | MGLL | Q99685 | 2/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.53 |
| ▸ | MAOB | P27338 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | MGAT2 | Q10469 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29957951 | 0.91 | MGLL (0.53) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL29957722 | 0.87 | NPC1 (0.60) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL29956641 | 0.86 | CASP3 (0.53) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL285633 | 0.85 | RAB9A (0.60) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL29950689 | 0.85 | NPC1 (0.64) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL13529179 | 0.84 | CASP3 (0.56) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL26030821 | 0.84 | CASP3 (0.62) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL29951619 | 0.84 | TACR3 (0.56) | MGLLRAB9ANPC1MAOBPOLB | |
| SCHEMBL27491709 | 0.83 | MAOB (0.58) | CASP3MGLLRAB9ANPC1MAOB | |
| SCHEMBL31167281 | 0.82 | NPC1 (0.57) | CASP3MGLLRAB9ANPC1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |